7.30 – 9.00: Breakfast
9.00 – 10.45: p53 and Family Members (Eric Eldering and Arturo Sala)
Jerry Chipuk: Direct Activation Of Bax By p53 Mediates Mitochondrial Membrane Permeabilization And Apoptosis.
W. Brent Derry: Assembling the p53 network in C. elegans by functional genomics.
Anastasis Stephanou: STAT1: a novel regulator of the apoptotic programme.
Miriam Erlacher: PUMA/bbc3, a key mediator of p53-induced apoptosis.
Hakan Akca: Cytokine-mediated induction of p53 and p21 is suppressed by EGF and insulin .
Vincenzo De Laurenzi: Identification of proteins regulating p73 function.
10.45 – 11.15: Coffee break
11.15 – 13.15: Cancer I (Michel Hahne and Brent Derry)
Peter Daniel: Synergy between TRAIL and DNA damaging tumor therapies depends on Bax but not Bak.
Monica Zerilli: Th2 cytokines induce chemotherapy resistance in epithelial tumors via PI3K/AKT pathway.
Engin Ulukaya: Response of lung cancer patients to cisplatin-based anti-cancer treatments: Effects on the levels of cleaved cytokeratin 18 and sFas .
Kerstin Bellmann: The counteracting roles of the kinases Akt/PKB and p38 in c-Myc dependent apoptosis.
Emma Sanzari: PED controls B-chronic lymphocytic leukaemia cell apoptosis
Arturo Sala: B-MYB regulates the stress response though direct transactivation of key survival genes.
Satoshi Inoue: Histone deacetylase inhibitors potentiate TNF-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in lymphoid malignancies.
13.15 – 15.00: Lunch
15.00-16.30: Free Time
16.30-18.00: Cancer II (Peter Daniel and Engin Ulukaya)
Lourdes Planelles: Development of hyperplasia in aged APRIL transgenic mice.
Paul Chen: A Role for BAFF in Tumour Immunity.
Tobias Haas: Caspase-8 recruitment to and activation at the DISC is critical for sensitisation of human hepatocellular carcinoma cells to TRAIL-induced apoptosis by chemotherapeutic drugs.
Eric Eldering: CD40 stimulation increases both the anti- and pro-apoptotic protein profile of B-CLL cells and renders them sensitive to autologous CTL-attack.
Till Wenger: Lentiviral expression of TRAIL in human tumor cells.
18.00-20.00: Posters 29-55
20.00: Dinner