8:00 – 9:00 Breakfast

9:15 – 11:00 Regulation of cell death 2: by Bcl-2 family proteins (Jan Paul Medema, Marion MacFarlane)

Andreas Villunger: BMF: A PROAPOPTOTIC BH3-ONLY PROTEIN REGULATED BY INTERACTION WITH THE MYOSIN V ACTIN MOTOR COMPLEX, ACTIVATED BY ANOIKIS

Arlette Werner: DEFINING THE MECHANISM OF ACTION OF BFL-1,  A NOVEL INHIBITOR OF BID

Pilar Justo: MODULATION OF ACETAMINOPHEN INDUCED APOPTOSIS IN CULTURED MURINE TUBULAR EPITHELIAL CELLS BY BclxL AND INHIBITORS OF CASPASES

Paul Coffer: THE FORKHEAD TRANSCRIPTION FACTOR FKHR-L1 IS A CRITICAL EFFECTOR OF CELL DEATH INDUCED BY SURVIVAL FACTOR WITHDRAWAL

Barbara Marinari: Vav exchange factor blockS CD4-mediated signals, inducing Bax increase and mitochondrial damage

Penny  Lovat: GADD153 AND BAK:NOVEL MOLECULAR TARGETS OF FENRETINIDE-INDUCED APOPTOSIS

 

11:00 – 11:30 Coffee break

11:45 – 13:15 Regulation of cell death 3: at mitochondrial level and beyond (Marion MacFarlane, Jan Paul Medema)

Nigel Waterhouse: Single cell analysis of reactive oxygen species during mitochondrial outer membrane permeabiliSation

Geert Van Loo: Identification of tBid-induced release of mitochondrial proteins. Role of endonuclease G and Omi/HtrA2 in the apoptotic process

Marion MacFarlane: TRAIL-INDUCED APOPTOSIS RESULTS IN RAPID RELEASE OF SMAC AND ITS SUBSEQUENT DEGRADATION VIA THE UBIQUITIN-PROTEIN LIGASE ACTIVITY OF XIAP

John Silke: THE ROLE OF XIAP AND DIABLO/SMAC IN APOPTOSIS

Marie-Louise Brezniceanu:  IDENTIFICATION OF MAMMALIAN PROTEINS INHIBITING APOPTOSIS DOWNSTREAM OF CYTOCHROME C RELEASE

Klaus Schulze-Osthoff: Ionizing radiation but not cancer drugs causes G2/M cell cycle arrest and failure to activate the apoptotic pathway in breast carcinoma cells

 

13:15 – 15:00 Lunch

15:00 – 16:45 Regulation of cell death 4: Novel mechanisms (Eric Baehrecke, Nigel Waterhouse)

Gerolama Condorelli: MULTIPLE MEMBERS OF THE MITOGEN ACTIVATED PROTEIN KINASE FAMILY ARE NECESSARY FOR PED/PEA-15 ANTI-APOPTOTIC FUNCTION

Martin Leverkus: RESISTANCE TO TRAIL INDUCED APOPTOSIS IN PRIMARY KERATINOCYTES: A ROLE FOR EFFECTOR CASPASE INHIBITION

Grisha Pirianov: Rac is Involved in the Apoptotic Response of N1E-115 Neuroblastoma Cells to Staurosporine, but not to Ceramide

Eric Baehrecke: GENETIC REGULATION OF PROGRAMMED CELL DEATH DURING DROSOPHILA DEVELOPMENT

Arturo Sala: UNVEILING THE APOLIPOPROTEIN J SIGNALLING NETWORK: IMPLICATIONS FOR CELL SURVIVAL, PROLIFERATION AND ONCOGENESIS

Maria Fiammetta Romano: A.I.R. (APOPTOSIS-INDUCED AND REGULATOR), A NOVEL GENE THAT REGULATES APOPTOSIS

 

16.45 – 19.45 Poster Session with drinks and tapas sponsored by

20:00 Dinner