9.00-11.15 Death in Cancer (Jan Paul Medema and Ricky Johnstone)

Ricky Johnstone: Defining the apoptotic pathways underlying histone deacytelase inhibitor-mediated tumor therapy.

Elza de Bruin: Role of intrinsic and radiotherapy-induced apoptosis in rectal cancer patients.

Dario Lombardi: Cytotoxic activity of normal and cancer neural stem cells through the production of death receptor ligands.

Arturo Sala: The double life of ApoJ/clusterin: an antiapoptotic protein inhibitor of neuroblastoma metastasis.

Mileidys Perez Alea: Cancer stem cells contribute to the aggressive behaviour of human epithelial colon cancer.

Maria Giovanna Francipane: Autocrine production of IL-4 confers resistance to chemotherapy and CD95-induced cell death in cancer cells.

Valeria Coppola: miR-15 and miR-16 induce apoptosis by targeting BCL2 in prostate cancer.

 

11.15-11.45  coffee break

11.45-13.15 Alternative Pathways (Eric Baehrecke and Marja Jäättelä)

Catherine Stenson: A more serine way to die? Investigating the role of serine proteases in leukaemic cell death.

Mads Gyrd-Hansen: Apoptosome-independent activation of lysosomal cell death pathway by caspase-9.

Mads Daugaard: Hsp70-2 controls the expression level of a potent cancer cell survival protein, Lens Epithelium Derived Growth Factor (LEDGF/p75).

Mélanie Denizot: Autophagy is involved in CD4+ T cell death triggered by HIV-1 envelope proteins.

Katja Simon: Autophagy and the immune system in vivo.

 

13.15-14.45  lunch

14.45-16.00 Alternative Pathways (discussion session)

Eric Baehrecke: Genetic regulation of autophagic programmed cell death.

Marja Jäättelä: Disruption of the lysosomal pH gradient combined with the inhibition of autophagosome formation, a new strategy for anti-cancer therapy?

Discussion on the role of alternative pathways in cell death

 

16.00-20.00 Poster Session + drinks

Posters (names A-L)

20.00 dinner