7.30 – 9.00:  Breakfast

9.00 – 11.00: Immunology and Inflammation (Jan Paul Medema and John Silke)

Douglas Green: A Physiological Function for TRAIL.

Katharina Simon: Fas Ligand (FasL): an adjuvant to generate monoclonal antibodies that reject tumour .

Lages Alves: Early induction of BH3-only protein Noxa in naïve CD8+ T cells after TCR triggering.

Michel Hahne: Distinct functions for APRIL in regulation of humoral responses.

Ajoy Samraj: The tyrosine kinase Lck is a positive regulator of the mitochondrial apoptosis pathway by regulating Bak expression.

Alberto Bosque: The mitochondrial apoptotic pathway in perforin/granzyme-induced apoptosis mediated by CTL effectors.

 

11.00 – 11.30: Coffee break

11.30 – 12.45: Mitochondrial Pathways (Marion MacFarlane and Giorgio Stassi)

Andreas Villunger: An essential role for the BH3-only protein Bim in the establishment of central tolerance.

Christoph Borner: Shuttling Bax from the cytosol to mitochondria: a complex business involving N- and C-termini.

Gavin McStay: Identification of a novel post-translational modification of Apaf-1 after apoptosome activation.

Cristina Muñoz-Pinedo: Mitochondrial intermembrane space proteins are released in a single step during apoptosis.

 

12.45 – 14.00: Lunch

14.00 – 19.00: Excursion to Istanbul

20.00: Dinner