9:00am – 10:30am Session V: Bcl2-family in development (Katja Simon)

Eric Eldering Darwinistic selection following T cell activation: the Noxa/Mcl-1 axis constitues a survival threshold set by TCR affinity and IL-2 signaling

Felix M. Wensveen BH3-only protein Noxa mediates selection of high-affinity clones during antigen-driven interclonal B cell competition

Daniela Bertele The role of pro-apoptotic BH3-only proteins during engraftment and reconstitution of human haematopoietic stem cells

Claudia Woess Investigating the role of BH3-only proteins in B cell development

Paul G Ekert The Regulation Of Puma In Life And Death

 

10:30am – 11:00am Coffee Break

11:00am – 12:15pm Session VI: Bcl2-family in cancer (Ricky W Johnstone)

Florian Baumgartner Investigating the Role of the BH3-only Proteins Bim and Bmf in Mammary Gland Development, Cancer and Metastasis

Michaela Waibel Targeting pro-survival Bcl-2 proteins in haematological malignancies driven by activated mutant JAK2.

Seamus J Martin Bcl-2 family proteins as modulators of oncogenic Ras-induced cell death

Cassandra Vandenberg Apoptosis-promoted tumorigenesis: Puma-driven leukocyte death allows thymic lymphomagenesis

 

Lunch 12:15pm 1:45pm

Social Afternoon: Trip to Copenhagen The bus leaves at 1:45pm and we return at ca. 11:30pm