9.00 – 11.00 Inflammation
Chairs: Seamus Martin, Henning Walczak
09.00 – 09.15 Introduction by Seamus J. Martin
09.15 – 09.30 Seamus J. Martin: Interactions between dying cells and the immune system
09.30 – 09.45 W. Wei-Lynn Wong: Inflammation before Death: Cytokine regulation by IAPs and RIPKs
09.45 – 10.00 Tom Vanden Berghe: Systematic analysis of inflammatory and cell death components in LPS-induced shock reveals correlation between survival and intestinal goblet cell hyperplasia
10.00 – 10.15 James Rickard: Necroptosis and macrophages in Sharpin dermatitis – a deadly liaison?
10.15 – 10.30 Brian Ferguson: Innate immune DNA sensing by DNA-PK
10.30 – 10.45 Anastasis Stephanou: Blocking IL-17 signalling reduces apoptosis following myocardial ischaemia/reperfusion injury
10.45 – 11.00 Ursina Gurzeler: Regulation Of FasL- And TNFα-Induced Cell Death In Murine Neutrophils
11.00 – 11.30 Coffee break
11.30 – 12.30 Autophagy
Chairs: Katja Simon, Monika Mortensen
11.30 – 11.45 Introduction by Katja Simon
11.45 – 12.00 Yang Liu: A Novel Form of Cell Death Triggered by an Autophagy-Inducing Beclin 1 Peptide
12.00 – 12.15 Monika Mortensen: The role of autophagy in human healthy hematopoietic and acute myeloid leukemia cells
12.15 – 12.30 Alec Watson: A role for autophagy in hematopoetic stem cell homeostasis and fate
13.00 – 14.30 Lunch
15.00 – 16.15 Autophagy
Chairs: Katja Simon, Monika Mortensen
15.00 – 15.15 Kanchan Phadwal: Is macroautophagy a safeguard mechanism against immunosenescence?
15.15 – 15.30 Federica Albiero: Crosstalk between autophagy and the ubiquitin proteasome system: Role of AMBRA1-DDB1 interaction.
15.30 – 15.45 Jennifer Martinez: LC3-associated phagocytosis mediates IFN-α secretion in response to DNA-immune complexes
15.45 – 16.00 Sara Galavotti: Role of the autophagy-associated factors DRAM1 and p62 in glioblastoma stem cells
16.00 – 16.15 Pierre-Emmanuel Joubert: Chikungunya virus-induced autophagy delays apoptosis via the induction of ER stress and generation of reactive oxygen species.
16.15 – 16.45 Coffee break
16.45 – 18.30 Cell death and metabolism
Chairs: Cristina Muñoz-Pinedo, Mads Daugaard
16.45 – 17.00 Introduction by Ameeta Kelekar
17.00 – 17.15 Amanda J. Stranks: Autophagy deficiency in myeloid cells leads to metabolic changes
17.15 – 17.30 Cristina Muñoz-Pinedo: Mechanisms of cell death induced by inhibition of glucose metabolism
17.30 – 17.45 Gabriel Leprivier: The eEF2 kinase is a conserved mediator of tumor adaptation to metabolic stress
17.45 – 18.00 Mads Daugaard: Control of ROS generation as a bona fide tumor suppressor mechanism
18.15 – 18-30 Lisette Potze: Novel mechanistic aspects of Betulinic acid-induced cell death
19.00 – 20.30 Dinner
20.30 – 22.00 Poster session II + Bar talk (Wayne Patton, Enzo Life Sciences)