9:00am – 10:30am Session VII: Apoptosis and ubiquitin (Henning Walczak)

Pascal Meier Regulation of apoptosis by ubiquitin and ubiquitin-like proteins

Mike Hupe cIAPs inhibit a cryptic CD95-induced cell death by limiting RIP1 kinase recruitmen

Inge Verbrugge MARCH ubiquitin ligases dictate TRAIL-Receptor 1 membrane expression and TRAIL sensitivity in human tumor cells

Christophe Le Clorennec The Role of the new c-FLIP binding protein Ku70 in Death Receptor mediated apoptosis: The DUB Ku70: Novel regulator of c-FLIP function.

Philipp Jost Apoptotic Regulation by IAPs in the Liver

 

10:30am – 11:00am Coffee Break

11:00am – 12:30pm Session VIII: Caspases and Apoptosis I (John Silke)

Cristina Muñoz-Pinedo DeathBase: a database on structure, evolution and function of proteins involved in apoptosis and other forms of cell death.

Thomas Kaufmann Analysing the Crosstalk from the Death Receptor to the Mitochondrial Apoptotic Pathway

Maike A Laussmann Proteasome inhibition induces FADD-dependent caspase-8 activation

Lisa Bouchier-Hayes Characterization of Cytoplasmic Caspase-2 Activation by Induced Proximity

Andreas Villunger Investigating the enigma of caspase-2

 

Lunch 12:30pm 2:30pm

2:30pm – 4:00pm Session IX: Caspases and Apoptosis II (Seamus Martin)

Rosario Yerbes Cellular FLIPL plays a survival role and regulates morphogenesis in breast epithelial cells.

Ueli Nachbur Kupffer cells, canaries in the coal mine of liver damage or ticking time bombs?

Zofia Kirejczyk Proapoptotic signalling through Toll-like receptor-3 involves TRIF-dependent activation of caspase-8 and is under the control of inhibitor of apoptosis proteins in melanoma cells

Julian Pardo Pleiotropism of granzyme B-induced cell death; A means of the host to counter pathogen (tumor) evasion strategies of Tc cell-mediated recovery

Sean Cullen Suppression of interleukin-33 bioactivity through proteolysis by apoptotic caspases.

 

4:00pm – 4:30pm Coffee Break

4:30pm – 6:00pm Session X: Autophagy and alternative cell death (Jan Paul Medema)

Stephen Tait Resistance to caspase-independent cell death requires persistence of intact mitochondria

Thomas Kirkegaard Hsp70 stabilizes lysosomes and reverts Niemann-Pick disease-associated pathology

Amanda Stranks Characterisation of autophagy deficient Atg 7-/- Macrophages

Anne Keldsbo Autophagy induced by DNA damaging agents.

Monika Mortensen Spontaneous development of leukaemia in the absence of autophagy (Atg7) in vivo

 

Poster Session II 6:00pm 8:00pm

8pm – 10pm Dinner

BAR…..