8.45-11.00 BH3 molecules (Andreas Villunger and Philippe Bouillet)
Philippe Bouillet: Mouse models to decipher the role of the BH3-only proteins in triggering apoptosis.
Verana Labi: The BH3-only protein Bmf has overlapping functions with Bim during cell death induction and B-cell development.
Paul Ekert: Cell death provoked by loss of Interleukin-3 signalling is independent of Bad, Bim, and PI3 Kinase/AKT, but depends in part on Puma.
Stephen Tait: Unconventional ubiquitination of Bid is required for its pro-apoptotic activity.
Miriam Erlacher: Combined loss of Bim and Puma mirrors the effects of Bcl-2 overexpression in some but not all forms of cell death.
Eric Eldering: Distinct expression levels of Noxa in peripheral versus lymph node chronic lymphocytic leukemia cells are linked with survival capacity.
Nuno Lages Alves: The Noxa/Mcl-1 axis regulates susceptibility to apoptosis under glucose limitation in dividing T cells.
Bernhard Gillisen: Nbk induces apoptosis via an ER pathway in a Bax-dependent manner.
11.00-11.30 coffee break
11.30-13.30 Mitochondrial Structure and Death
Lisa Bouchier-Hayes: Bax-mediated membrane permeabilization can occur in cells in the absence of mitochondrial membrane proteins.
Jerry Chipuk: Mitochondrial outer membrane permeabilization is directly regulated by the mitochondrial fission machinery.
Cristina Muñoz-Pinedo: Coordinate release of mitochondrial inter-membrane space proteins during apoptosis revealed by real time single cell analysis.
Patrice Petit: Cloning of the human cardiolipin synthase and effects of its knowkdown on cell death progression: a switch between apoptosis and necrosis.
Eric C.C. Cheung: Dissociating the dual roles of apoptosis inducing factor (AIF) in apoptosis and maintaining mitochondrial structure.
Franziska Mullauer: Betulinic acid induced cell death in cancer cells.
David Dickens: Identification of MAP4K3 as a putative tumor suppressor using an RNAi screen.
13.30-15.00 lunch
15.00-16.00 BH3-Mitochondria (discussion session)
16.00-20.00 Poster Session + drinks
Posters (names M-Z)
20.00 dinner