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8.45-11.00 BH3 molecules (Andreas Villunger and Philippe Bouillet)

Philippe Bouillet: Mouse models to decipher the role of the BH3-only proteins in triggering apoptosis.

Verana Labi: The BH3-only protein Bmf has overlapping functions with Bim during cell death induction and B-cell development.

Paul Ekert: Cell death provoked by loss of Interleukin-3 signalling is independent of Bad, Bim, and PI3 Kinase/AKT, but depends in part on Puma.

Stephen Tait: Unconventional ubiquitination of Bid is required for its pro-apoptotic activity.

Miriam Erlacher: Combined loss of Bim and Puma mirrors the effects of Bcl-2 overexpression in some but not all forms of cell death.

Eric Eldering: Distinct expression levels of Noxa in peripheral versus lymph node chronic lymphocytic leukemia cells are linked with survival capacity.

Nuno Lages Alves: The Noxa/Mcl-1 axis regulates susceptibility to apoptosis under glucose limitation in dividing T cells.

Bernhard Gillisen: Nbk induces apoptosis via an ER pathway in a Bax-dependent manner.

 

11.00-11.30 coffee break

11.30-13.30 Mitochondrial Structure and Death

Lisa Bouchier-Hayes: Bax-mediated membrane permeabilization can occur in cells in the absence of mitochondrial membrane proteins.

Jerry Chipuk: Mitochondrial outer membrane permeabilization is directly regulated by the mitochondrial fission machinery.

Cristina Muñoz-Pinedo: Coordinate release of mitochondrial inter-membrane space proteins during apoptosis revealed by real time single cell analysis.

Patrice Petit: Cloning of the human cardiolipin synthase and effects of its knowkdown on cell death progression: a switch between apoptosis and necrosis.

Eric C.C. Cheung: Dissociating the dual roles of apoptosis inducing factor (AIF) in apoptosis and maintaining mitochondrial structure.

Franziska Mullauer: Betulinic acid induced cell death in cancer cells.

David Dickens: Identification of MAP4K3 as a putative tumor suppressor using an RNAi screen.

 

13.30-15.00 lunch

15.00-16.00 BH3-Mitochondria (discussion session)

16.00-20.00 Poster Session + drinks

Posters (names M-Z)

20.00 dinner